Division of Biochemistry

We develop new applied biomaterials by investigating biological processes such as recognition and sensing from a chemical perspective.

Prof FUTAKI, Shiroh (D Pharm Sc)

The ultimate goal of our research is the regulation of cellular functions by designed peptides and proteins. Current projects include “Development of membrane permeable peptide vectors”, “Design of peptides inducing structural changes of the plasma membrane”, and “Creation of nucleic acids-binding proteins with desired sequence specificities and control of cellular functions”.

Prof YAMAGUCHI, Shinjiro (D Agr)

A group of small molecules, called plant hormones, play an important role in growth and environmental responses of plants. We take chemical and biological approaches to understand how hormones are made and act in plants. We also try to identify new hormone-like compounds that have been implicated in studies on mutants.

 

We are interested in the signal transduction and gene expression for the regulation of plant morphogenesis. Targets of our study include the involvement of phospholipid signaling in cell morphogenesis, the cytokinin signal transduction mediated by the transcription factor ARR1, and the regulatory mechanism of plant morphogenesis by the COP9 signalosome.

The Arabidopsis phospholipid signaling
factor PIP5K3 specifically localizing at
the tips of elongating root hairs.

Prof UESUGI, Motonari (D Pharm Sc)

Small organic molecules have been utilized to improve human health and to elucidate the secrets of life. Discovery or design of small organic molecules with unique biological activity permits small-molecule-initiated exploration of cells and living organisms. Our laboratory has been discovering small organic molecules that modulate a range of biological events and use them as tools to explore and control biological events.