21世紀COEプログラム 研究者情報     [ English | Japanese ] 富岡　清（とみおか　きよし） 京都大学 大学院薬学研究科 創薬科学専攻 薬品合成化学分野 教授 薬学博士 http://www.pharm.kyoto-u.ac.jp/tomioka/index.html E-mail: tomioka@pharm.kyoto-u.ac.jp Tel: +81-075-753-4553 Fax: +81-075-753-4604
研究・教育歴 1976.3 東京大学大学院薬学系研究科博士課程修了（薬学博士） 1976.5 米国コロラド州立大学化学科博士研究員（A. I. Meyers 教授） 1978.5 東京大学薬学部助手（薬品製造化学 古賀憲司教授） 1983.8 東京大学薬学部助教授 1992.4 大阪大学産業科学研究所教授 1996.1 京都大学薬学部併任教授 1996.4 京都大学薬学部教授 1999.4~ 京都大学大学院薬学研究科教授（薬品合成化学） 専門分野 有機化学、創薬化学、不斉合成、分子集合化学 主な研究テーマ 未来型不斉触媒反応の開拓 立体化学制御の基礎概念と設計 抗腫瘍化合物の全合成と生物有機化学 分子集合系の構築 主な論文・著書 Hidetaka Fujihara, Kazushige Nagai and Kiyoshi Tomioka, Copper-Amidophosphine Catalyst in Asymmetric Addition of Organozinc to Imines Katsumi Nishimura, Masashi Ono, Yasuo Nagaoka, and Kiyoshi Tomioka, Catalytic Enantioselective Protonation of Lithium Ester Enolates Generated by Conjugate Addition of Arylthiolate to Enoates Kiyoshi Tomioka, Yoshito Shioya, Yasuo Nagaoka, and Ken-ichi Yamada, Electronic and Steric Control in Regioselective Addition Reactions of Organolithium Reagents with Enaldimines Masashi Ono, Katsumi Nishimura, Hiroshi Tsubouchi, Yasuo Nagaoka, and Kiyoshi Tomioka, Total Synthesis of (-)-Neplanocin A Using Lithium Thiolate-Initiated MichaelﾐAldol Tandem Cyclization Reaction Kiyoshi Tomioka, Takaaki Sumiyoshi, Shinobu Narui, Yasuo Nagaoka, Akira Iida, Yoshihisa Miwa, Tooru Taga, Minoru Nakano, and Tetsuro Handa, Molecular Assembly and Gelating Behaviour of Didodecanoylamides of α,ω-Alkylidene-diamines Katsumi Nishimura and Kiyoshi Tomioka, Chiral Amino Ether-Controlled Catalytic Enantioselective Arylthiol Conjugate Addition to a,b-Unsaturated Esters and Ketones: Scope, Structural Requirements, and Mechanistic Implications Yasuo Nagaoka, Hideki Inoue, Nawal El-Kossi, and Kiyoshi Tomioka , Synthesis and Application of Chiral Bisphosphines through Lithiation-Conjugate Addition Tandem Cyclization of Chiral a,b,c,y-Unsaturated Bisphosphine Oxide Hideki Inoue, Yasuo Nagaoka and Kiyoshi Tomioka, A New Methodology for Synthesis of A Chiral Phosphinocarboxylic Acid Through Michael Cyclization-Aldol Tandem Reaction of Chiral a,b,c,y-Unsaturated Bisphosphine Oxide and Application in Palladium-Catalyzed Asymmetric Allylic Alkylation Masami Kuriyama, Kazushige Nagai, Ken-ichi Yamada, Yoshinao Miwa, Tooru Taga and Kiyoshi Tomioka, Hemilabile Amidomonophosphine Ligand-Rhodium(I) Complex-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to Cycloalkenones Hirohisa Doi, Takeo Sakai, Mayu Iguchi, Ken-ichi Yamada, and Kiyoshi Tomioka, Chiral Ligand-Controlled Asymmetric Conjugate Addition of Lithium Amides to Enoates Takaaki Sumiyoshi, Katsumi Nishimura, Minoru Nakano, Tetsuro Handa, Yoshihisa Miwa, and Kiyoshi Tomioka, Molecular Assembly of C2-Symmetric Bis-(2S)-2-methyldodecanoylamides of α,ω-Alkylidenediamines into Coiled Coil and Twisted Ribbon Aggregates Takahiro Soeta, Kazushige Nagai, Hidetaka Fujihara, Masami Kuriyama, and Kiyoshi Tomioka , Asymmetric Alkylation of N-Toluenesulfonylimines with Dialkylzinc Reagents Catalyzed by Copper-Chiral Amidophosphine Ken-ichi Yamada, Yasutomo Yamamoto, Masaru Maekawa, and Kiyoshi Tomioka, Introduction of Functionalized C1, C2, and C3 Units to Imines through the Dimethylzinc-Air-Initiated Radical Addition Mitsuaki Yamashita, Ken-ichi Yamada, and Kiyoshi Tomioka, Construction of Arene-Fused-Piperidine Motifs by Asymmetric Addition of 2-Trityl-oxymethylaryllithiums to Nitroalkenes: the Asymmetric Synthesis of A-86929.
Update: April 04, 2004